Toothbrushes carry various viruses, including bacteriophages. These viruses are attracting attention for their potential to treat antibiotic-resistant infections, according to a study recently published in Frontiers in Microbiomes.
Researchers from the Northwestern University McCormick School of Engineering have revealed the diversity of bacteriophages in household environments, potentially improving our understanding of indoor microbial ecosystems.
"We want to look at all the functions these viruses might have and figure out how we can use them," Erica Hartmann, PhD, an associate professor of civil and environmental engineering, said in a university story dated October 9.
The study builds on previous research conducted by Hartmann. Previously Hartmann and her team asked people to submit used toothbrushes and swabs with samples collected from their showerhead.
After characterizing the bacteria, Harmann used DNA sequencing to examine the bacteria. She was surprised to find that the samples were made up of more than 600 different viruses. Hartmann noted the presence of mycobacteriophage more than any other type of phage.
Mycobacteriophage infect mycobacteria, a pathogenic species that can cause diseases like leprosy, tuberculosis, and chronic lung infection.
"We could envision taking these mycobacteriophage and using them as a way to clean pathogens out of your plumbing system," Hartmann said. "We want to look at all the functions these viruses might have and figure out how we can use them."
Hartmann added that the microbes aren't something to worry about. People, however, should regularly change their toothbrush. Hartmann isn't a fan of antimicrobial toothbrushes, the use of which can lead to antimicrobial resistance, she said.
"Microbes are everywhere, and the vast majority of them will not make us sick. The more you attack them with disinfectants, the more they are likely to develop resistance or become more difficult to treat. We should all just embrace them," Hartmann added.
